Of the more than 100,000 Pulmonary Embolism (PE) cases that occur each year in the United States, about 30 percent of those left untreated result in death -- which occurs most often in the first few hours of the event. P3T PA is the only contrast injection application of its kind that has proven to increase the percentage of diagnostic CTPA studies to rule out PE. The product has also been shown to result in better contrast enhancement of the pulmonary arteries when compared to standard exams.*
CTPA is the gold standard to rule out PE. However, when a study is classified as sub-diagnostic, physicians must choose to reimage, to conduct additional tests or to proceed with treatment.
In a recent Albany Medical Center abstract², 30% of the PE studies conducted in the Emergency Department classified as suboptimal. Patients with suboptimal interpretations were subjected to additional imaging studies and/or received medical therapy. In some cases, patients were admitted to the hospital for further PE diagnosis consideration. As a result, the suboptimal interpretations substantially impacted healthcare resource utilization and increased healthcare costs.
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| Example of Poor Enhancement |
Example of Appropriate Enhancement |
Images courtesy of University of Pittsburgh Medical Center (UPMC)
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"Achieving a diagnostic CT image for pulmonary embolism, without limitations, helps the hospital and emergency department in a number of important ways -- with efficiency, patient care, and cost savings."
Joan Lacomis, M.D.
Clinical Professor Radiology
UPMC, University of Pittsburgh Medical Center
(Comment based solely on user experiences)
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1. Presented at Society of Thoracic Radiology (2008) Poster Session; Christopher R. Deible MD, PhD. Information and images provided through the courtesy of the University of Pittsburgh. Used by permission.
* At a slightly higher contrast dose than standard prototcol (80ml)
2. Abstract: Patient Outcomes and Resource Utilization for Emergency Department Patients with Suspected Pulmonary Embolism and Initial Chest Computer Tomography Angiography. Studies Deemed Suboptimal for Interpretation; Weinstein, JM, Burton, JH, ED Albany Medical Center.